Introduction
Esophagus
is the narrow muscular tube that runs from your mouth to stomach, forming
passage to food you eat. It can be the site one of the lethal cancer of your
body, called esophageal carcinoma or cancer of esophagus. It commonly begins to
develop in the inner lining of your esophagus, but may involve other outer
layers. It is malignant and have tendency to spread beyond esophagus to distant
parts and organs of your body. Esophageal has very slow progress with minimal early
symptoms. This one factor makes survival rate after treatment very low. By that
time it is commonly diagnosed it has already spread to other parts of your body
or to adjacent structure with serious and lethal effects.
Most
common location of your esophageal cancer is lower third of the tube like
structure.
The
common factors which predict development of esophageal cancer are heavy alcohol
and smoking. They act as chronic irritant in your cancerous esophagus.
Incidence of
esophageal cancer ; The esophageal cancer has been encountered more commonly
between age of 65 years-75 years. Men are effected more than women at ratio 4:1
worldwide. Being tenth most common cause of death due to cancer all over globe.
It is very rarely seen in children.
Risk
factors
Smoking of
cigarettes, cigars and pipes are very strong provoking agents for your
esophageal cancer. Among the leading risk factor smoking has been found to be
greater risk in squamous cell carcinoma than in adenocarcinoma. The mechanism
involves the release of carcinogens from tobacco smoke such as nitrosamines.
These may initiate esophageal cancer growth in squamous cells layer of your
esophagus. Duration of your smoking habit plays significant factor to increase
your risk for esophageal malignancy.
Alcohol in excess
has been risk factor for several cancers, likewise it plays its role in making
you more susceptible for esophageal cancer. If you drink alcohol in larger
volume even for short duration your risk for esophageal cancer increases
greatly. The same will not be true if you drink alcohol in moderation for
longer periods. Heavy drinking called binge together with cigarette smoking
enhances your risk for squamous cells carcinoma of esophagus.
GERD syndrome is
acquired condition in which acid from stomach reflexes back into esophagus
causing chronic erosion at lower part of your esophagus. This constant
irritation damages the squamous cells of esophagus converting them into cancer
developing cells in long term. Adenocarcinoma is the type of esophageal cancer
which grows due to this abnormality. Hyperacidity in lower esophagus thus can
create risk for you esophageal cancer.
Barret’s esophagus is precancerous condition
developing as result of acid reflux into esophagus from your stomach. During
long standing exposure of the cells of lower esophagus to stomach content,
changes into glandular columnar type. This cellular change or dysphasia has great risk for esophagus cancer of
adenocarcinoma type.
Obesity is risk
for your developing esophageal cancer. This is attributed to gastro esophageal
reflux. The heavier the weight you carry will put more intra-abdominal pressure
on gastro-esophageal junction. This factor increases GERD symptoms and
adeno-carcinoma risk.
Taking meals hot
and drinking hot liquids like tea, coffee increases your esophageal cancer
risk. Consumption of drinks with very high temperature has been shown as almost
four fold increase in risk of esophageal cancer (study done in high risk areas
of southern America, Argentine, Brazil, Uruguay and Paraguay).
Race of African
origin is almost 3% more at risk of esophageal cancer than whites.
Age factor
predisposes greatly on any chronic illness like cancer. Esophageal cancer will
appear more commonly after your 45th birth day. Risk becomes greater
at 65 years and more.
Esophageal cancer
is more common if you are living in developing country. This risk is based on
nutritional deficiencies because of scarcity of fresh fruits and vegetable in
your diet. There is more consumption of chewable tobacco, which is well known
strong risk for esophageal cancer. Squamous cell carcinoma is more prevalent in
dietary deficiency than adenocarcinoma variety.
Plummer Vinson
syndrome, a triad of iron deficiency anemia, inflammation of tongue and
dysphagia is linked with squamous cell cancer. It is an inherited condition(
passed on from one generation to another).
Radiotherapy to
your chest for some other cancer will put you in greater risk of esophageal
cancer in later years of life. Risk of esophageal cancer in women who were
treated for breast cancer by radiotherapy have shown two fold rise( study done
in southeast of England). Similar studies done in north America have revealed
that individual who underwent radiotherapy for Hodgkin’s lymphoma develop esophageal
cancer in 15-20 years time.
Males are more at
risk of developing esophageal cancer than women. It has occupational hazards,
smoking and alcohol playing co-factors. Exposure to trichloethylene and soot
dust(black dust particle fumes from coal, wood and oil burning) increases the
risk in men.
Life style Support and Prevention
Life
style and home remedies
Esophageal
cancer carries grave prognostic outcome. you will be detailed about the
seriousness of your esophageal carcinoma, the treatment and their side
effects.You should make yourself strong
and understanding about prevailing condition on you. Your own composure and
will to live and withstand all ill effects of your esophageal cancer can make
your survival better and less distressing and depressing. This situation may
create a change in your thought process how to cope. Making all positive changes
that were missing or getting rid of negative and harmful habits will improve
your health emotionally and physically, even with esophageal cancer.
The most common
factor which may have caused your esophageal cancer is acid reflex disease. The
best way to ease the difficulty is to avoid food which may increase your
stomach acidity. Eat food which are not spicy. Small frequent meals will also
combat the discomfort of GERD with your cancer. Sleeping with your headend
raised will greatly help prevent gastroesophageal reflux.
Swallowing
difficulty is most predominant complaint. Eat food item which are cooked to
texture suited for your extent of ease to swallow. Take liquids which will not
only be easy to swallow but also nutritious. Fresh fruit juices and milk shakes
can be your best choices.
Seek advise from
diet expert about how to cope with lack of deficiency of important vitamins
which may result because of your slow and difficult food intake. If your
oncologist/healthcare provider recommends take vitamin supplements to gain
strength.
With consultation
from your doctor keep active before and during treatment. This will keep your
blood circulation to optimum best.
The surgical
correction may cause dumping syndrome. This is combination of symptoms of
sweating, flushing and diarrhea after taking food. Eating balanced diet and
keeping lean weight will help you combat such distresses on long term
management.
Take ample rest
and avoid undue fatigue. Although the intense chemo, radiotherapy or surgical
remedies must have wear you out significantly, but studies have shown that
adopting some degree of physical exercise according to your suit will have dual
effects of physical as well as mental well being.
Quit smoking
forthwith. This will help you in your treatment outcome much better. It will
also enhance your longevity after esophageal cancer treatment.
Post treatment
consultation with your oncologist/healthcare provider should be maintained.
Follow up physical examination and investigation such as scanning or endoscopy
will indicate progress of effects of treatment, whether surgical or otherwise.
Alternative
medicine
The
alternative and complementary medicine has still not been proved to assist in
curing your cancer. It surly does help to comfort you from pain, stress and
physical and emotional fatigue from your esophageal cancer. They may also
counteract the side effects of your treatment. Some time and tested alternative
remedies in your esophageal cancer are ;
Acupuncture
technique comprises of piercing needles into specific pressure points in your
skin. This relieves symptoms of nausea, vomiting and pain accompanying your
esophageal cancer and its conventional therapies.
Massage will help
your tense muscle and nerves to relax. It involves gentle kneading, rubbing and
pressure massage of various parts of your body. It helps minimize anxiety,
fatigue and other emotional distresses of your esophageal cancer.
Meditation is
done with help of some expert guidance. Breathing exercises, practicing to
imagine peaceful surroundings happy events and images will bring back your
spiritual well being.
Yoga and tai chi
involves stretching and deep breathing exercise. It will keep you active during
your esophageal cancer treatment. It will also allay your stress and assist in
good sleep.
Aroma therapy is
based on the logic of soothing effects of scents on your mind. It uses scents
from plant extract, which will make you feel relaxed, control your nausea and
stress.
Coping
and Support
Stay connected to
your friends and close relatives besides your own family. Share and care role
will lift your own spirit. During recovery this will help you feel wanted and
involved in life. Seek help from them if you want.
Keep yourself
abreast with your esophageal cancer status. Asking your doctor in detail about
your esophageal cancer prognosis will give you sense of anticipation and
readiness of things to come and how to deal with them. Read magazine on
esophageal cancer. Search internet for latest information on your esophageal carcinoma.
Join group
specific for cancer or individuals with esophageal cancer. Listen to their
feelings and be open to express your own. It will generate new energy and
vitality of your thought process. Some of those discussions may bring new
revelation about coping and modality towards improvement in your daily life.
Acquire some
leisure habit. Having some fun will help enjoy life and stay calm. Chose
reading good material as hobby. It will keep you stay focused in present.
Volunteer work at
charity or helping out other cancer patient will make you feel happier and
useful to community even with your own esophageal cancer handicap.
Prevention
The
latest approach in medical practice is based on preventive aspect of any
disease or disability. Same is true for your esophageal cancer.
Quitting smoking
will remove one risk factor which will reduce risk from all kinds of cancers,
including esophageal cancer. It will also keep you protected from some other
health hazards of smoking. Sometimes giving up smoking is not that easy. There
are alternate or replacement substances available that will help you get rid or smoking in a way that would be
less demanding on you. Nicotine gums, skin
patches and spray have proven record in your efforts to give up smoking.
Binge drinking is
risk for esophageal cancer. Drinking in moderation and making it a strong habit
will minimize your risk for esophageal cancer.
Reduce weight if
your carry weight greater for your height. A BMI below 25 of standard should be
the aim. Avoid calories, exercise regularly daily for 15-20 minutes, five days
a week can easily help you achieve your goal. This one factor will counter your
GERD very effectively.
Diet rich in
fresh fruits and vegetables will go long way in helping weight management and
acid reflux disease. Though seems difficult to you to have at least five daily
servings of fruits and vegetables but its worth a price for preventing
esophageal cancer.
Having constant
complains of heartburn and stomach pain is risk for GERD. Get it treated in
proper way by your family doctor/healthcare provider. This is one of major rsik
for esophageal cancer and Barret’s esophagus.
Natural treatment
Black Cumin
Being used since the earliest
of times, Black cumin seeds (Nigella Sativa) have shown to be a remarkable cure
for many diseases. More than several studies have shown the specific benefit of
black cumin seeds in countering Esophageal cancer. The oil of the black cumin
seeds enhances the production of immune cells, anti-bodies and bone marrow. For
cancer therapies it has been shown to suppress tumor growth by 50%. Increased
immune response leads of better cancer targeting. Black cumin seeds can also
effectively help reduce the aggressiveness of cancer cells that lean on
angiogenesis.
Curcumin
The essential curcuminoid of
the spice turmeric, curcumin has been known for ages for its use in treating a
variety of illnesses. Its greatest benefit is its anti-carcinogenic effects.
Its effectiveness in treating esophageal and other cancers lies in its property
of causing apoptosis in cancerous cells without harming healthy cells. A study
conduction in 2009 on the effects of curcumin states that, " curcumin modulates growth of tumor cells through
regulation of multiple cell signaling pathways including cell proliferation
pathway (cyclin D1), cell survival pathway (Bcl-2, Bcl-xL, cFLIP, XIAP,
c-IAP1), caspase activation pathway (caspase-8, 3, 9), tumor suppressor pathway
(p53, p21) death receptor pathway (DR4, DR5), mitochondrial pathways, and protein
kinase pathway (JNK, Akt, and AMPK)"(Ravindran J., 2009).
Quercetin
Also known as Meletin and
Sophretin, Quercetin is a flavaniod, found in most plants, where onions, apples
and tea are some of its sources. Preliminary studies have shown the effectiveness
of Quercetin against cancer and other diseases, due to its anti-inflammatory
and anti-oxidant properties. Quercetin
can either be found in the skins of plants, or can be taken in supplement form.
Supplements range in doses of 50-500mg, although appropriate dosage of
Quercetin is unknown. Studies conducted in-vitro against the effectiveness of
Quercetin has shown positive results. It has been shown to foster apoptosis
(cell death) in cancerous cells. Knowledge of the benefits of Quercetin has been
limited though, due to the lack of conclusive research.
Resveratrol
Resveratrol, a natural phenol, is a chemical
that is produced naturally by plants when they are attacked by pathogens like
fungi and bacteria. The effectiveness of Resveratrol is a widely discussed
topic in human and animal studies. Initial research has shown the
anti-inflammatory and anti-cancer properties of this natural chemical. Sources
for Resveratrol are the skins of red grapes and other fruits. Preliminary
studies on rats treated with a carcinogen have shown that Resveratrol (1mg/kg
orally) has reduced the size and number of esophageal tumors to a substantial
degree (Hong T., 2002). It has also been shown to cause apoptosis in smooth
muscle and platelets (Huang Y., 2002).
Although
esophageal cancer has very poor prognosis. This is due to its early spread as
well as slow progress and late diagnosis. Even then as long as healthcare is
being given, you should keep your spirits high and take good care of yourself.
A good nutrition will play a major role in maintaining your energy level high.
With your doctors advise use supplements to boost any deficiency anticipated.
They have proven efficacy to help you overcome the stress and side effects of
your esophageal cancer and its treatment.