Friday, May 2, 2014

Bladder Cancer, Complication and Treatment










Complication


The common complications you can face because of bladder cancer, are listed in following ;

1)        Urinary tract Infection  : your urinary tract can develop block along path from kidneys to bladder or just at junction of ureters and bladder. Dilatation of pelvi-calyceal system, hydronephrosis may result. The resulting complication is infection of your urinary tract.

2)        Metastasis or spread :  Your bladder cancer can spread either locally to adjacent surrounding lymph nodes, bones and peritoneum, or to distant organs like lungs and liver. 

3)         Depression   : This is undeniable reality that after you are told about having bladder cancer, you life just gets into shock mode. Until you come to  terms depression sets in. You feel gloomy and hopeless.  

4)           Recurrence of cancer      :  This not uncommon happening, several years after treatment. Follow up of your bladder cancer hence becomes necessary.






Spread to outer layers.

 Pharmaceutical therapies

The modalities of treating your bladder cancer largely depend upon the stage or invasive nature of your tumor. It is to be managed by team of experts, includes RIA expert, surgeons and your consultant oncologist.  The following standard protocol may be applied alone or in combination, in your bladder cancer treatment;

1)     Surgery      :  This is generally applied for non-invasive superficial cancer of bladder. It is done by trans-urethral route. The technique is termed TURBT or transurethral resection of bladder tumor. It has shown very good results, but meticulous follow up is advised to you after your tumor has been removed. Although recurrence is not uncommon, but placing chemotherapeutic agent (Mitomycin C) inside your bladder at TURBT, will minimize the risk of recurrence.

2)      Radiation therapy  :  you may be subjected to high energy x-ray or ionizing radiation, which will kill or inhibit  the cancer cells growth in your bladder. Either applied as external radiation to your bladder, from machine outside or radiation in form of internal radioactive substance placement into the cancer or near it, through needle or probe or catheter.




Chemotherapy set

3)       Chemotherapy        :   The chemotherapy  applied in your bladder cancer can be intravesical. All the chemo medicine not only just kill cancer cells but the also damage the surrounding normal cells. This is done by means of tube passed through urethra into your cancerous bladder. Following chemo drugs will be given for your bladder cancer :

Ÿ                 Cisplatin
Ÿ                 Mitomycin 
Ÿ                 Methotrexate
Ÿ                 Vinblastine
Ÿ                 Doxorubicin

These chemotherapeutic agents are given intravenously in slow infusion. Whereas misogynic C is instilled or place locally into your bladder tumor mixed with sterilized distilled water.

Side effects of chemotherapy you may experience are, nausea ,vomiting, headaches, weakness , appetite, loss of hairs, loss of weight, marked lowering of immunity with risk of severe infection attacking your body. Irritation with bladder lining inflammation, anemia, thrombocytopenia(lowering platelets count) with easy bruising, oral thrush(fungal infection ),dry and soreness of skin, brittle nails, memory impairment.



Biological therapy         :   The principle of treatment is based on boosting your immune system to fight the aggressive and damaging cancer cells. You will receive BCG vaccine(bacillus calmette Guerin), locally instilled into your cancerous bladder. This is most suited in non-invasive, initial stages of your cancer. It also minimizes risk of recurrences. It enhances the immune system, which targets and kills your bladder cancer cells.


Ÿ  Interferon:  is yet another treatment ,which works in same manner as BCG, enhancing your immunity. It is produced in body naturally and synthetically manufactured Interferon µ2b is used to have the effect. The mode is instillation into cancer area of your bladder through intra-urethral tube.

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